Thomas R. O'Donnell

Posts Tagged ‘DNA’

This Iowa mom uses a scooter. This Olympian vaults hurdles. A rare condition links them.

In Uncategorized on February 11, 2016 at 7:20 am
Jill Viles (with her son, Martin) uses an electric scooter to get around. Patricia Lopes-Schliep is a world-class hurdler. The women have discovered they share a rare muscle condition. For Viles, it's part of the reason she can no longer walk. For Lopes-Schliep, it's part of the reason for her dominance on the track.

Jill Viles (with her son, Martin) uses an electric scooter to get around. Patricia Lopes-Schliep is a world-class hurdler. The women have discovered they share a rare muscle condition. For Viles, it’s part of the reason she can no longer walk. For Lopes-Schliep, it’s one reason for her dominance on the track. Image via the Toronto Star.

The idea seemed ludicrous: A muscle-bound world-class athlete and an Iowa mom with arms and legs reduced to sticks, sharing the same rare muscle condition.

When her sister suggested it, Jill Viles scoffed. “Who in a million years would possibly put together somebody who can’t walk and somebody who’s an Olympic hurdler?” Viles said this week from her home in Gowrie, in north-central Iowa

But doctors had been wrong before about Viles, who lost use of her legs several years ago. And the more she examined photos of Priscilla Lopes-Schliep, a Canadian who won bronze in 2008, the more she began to think her sister was right.

Looking a picture of Lopes-Schliep from the back, “it was absolutely my dad. It was something I had seen since I was a little girl,” said Viles, a Des Moines native. “Our family is connected to that picture and we have a mutation” in a gene that led to the unusual physique. “It’s uncanny.”

But did they really share a genetic hiccup? And if so, why did it put Jill Viles into a motorized scooter but made Priscilla Lopes-Schliep a track champion?

The search for answers led Viles onto another leg of an already remarkable tale of discovery. It’s a science story, but also a human-interest story that has gotten attention from across America and around the world.

The quest goes on. Viles is seeking donations to support research into the differences and similarities between her and Lopes-Schliep – the anti-Jill Viles – with the hope it could lead to new therapies, even for those suffering from more common muscle conditions. With enough donations, Viles also hopes to help others travel to consult with the world’s leading expert in her condition.

Read the rest of this entry »

Advertisements

A zombie tractor and ISU plant research’s new direction

In University research on April 14, 2014 at 6:30 am
The automated phenotyping robot, or as I call it, the zombie garden tractor: RTK-GPS, autosteer system, multiple 3-D digital camera.

The automated phenotyping robot (zombie garden tractor): RTK-GPS, autosteer system, multiple 3-D digital camera. (From a Patrick Schnable presentation)

The zombie garden tractor gets your attention.

The driverless machine can move through rows of sorghum, going for hours with only a GPS navigation brain to guide it. High-tech cameras, meanwhile, take three-dimensional photos of every sorghum plant it passes – a kind of Google Street View for fields.

More importantly, the unmanned machine represents Iowa State University’s push into phenomics, a research frontier that promises to reshape the way we grow the food and substances we count on.

Just as genomics researchers aim to understand a plant’s total genetic makeup – every letter in the long book of its DNA – and how it influences plant development, phenomics aims to understand plant phenotypes in similar depth.

A phenotype is the way an organism grows, appears and performs, given its genetic makeup, the environment it lives in, and how the two interact.

“What’s cool – and this is what makes it most interesting to me – is the interaction between genetics and environment,” said Patrick Schnable, an ISU distinguished professor of genetics.

Schnable leads ISU’s drive into phenomics research. He took over as director of the Plant Sciences Institute (PSI) in February with the charge to bring it (and the university) to international prominence in one or more research areas.

He’s targeting phenomics, knowing the field is ripe for discovery. Read the rest of this entry »

Urban Utopias

From Garden Cities to Smart Cities, the past and present of cities of the future.

Mary Murphy

Iowa and Beyond

Iowa Science Interface

A blog about research and STEM in the Hawkeye state

On Our Own

Sustainability in a Turbulent World

Miss Lou Acquiring Lore

Gallery of Life...

this is... The Neighborhood

the Story within the Story

Rare Metals Matter

A place to explore advances in rare metal material science and applications.

Indie Omnibus

A blog about research and STEM in the Hawkeye state

Paul Krugman

A blog about research and STEM in the Hawkeye state

tsmith

A blog about research and STEM in the Hawkeye state

Deixis Online

A blog about research and STEM in the Hawkeye state